Blastocyst is an embryo that has developed for five days after fertilization. The majority of Embryo transfers are performed on day 2 or day 3. As of late, improvement in culture condition and advanced incubators we were able to develop good blastocysts. Preliminary studies with new media and age in great responder lady have shown that ~50% of the treated eggs achieve blastocyst arrange.

Advantages of blastocyst culture:

• Better selection of the embryos to be transferred
• Limit the number of embryos to be transferred
• Eliminate the risk of multiple pregnancy
• Better implantation rate
• We can do PGD/PGS from this embryo

After the procedure

After the embryo transfer, you can resume normal daily activities. However, your ovaries may still be enlarged. Consider avoiding vigorous activity, which could cause discomfort.

Typical side effects include:

• Passing a small amount of clear or bloody fluid shortly after the procedure — due to the swabbing of the cervix before the embryo transfer
• Breast tenderness due to high estrogen levels
• Mild bloating
• Mild cramping
• Constipation

If you develop moderate or severe pain after the embryo transfer, contact your doctor. He or she will evaluate you for complications such as infection, twisting of an ovary (ovarian torsion) and severe ovarian hyperstimulation syndrome.

Results:

About 12 days to two weeks after egg retrieval, your doctor will test a sample of your blood to detect whether you’re pregnant.

• If you’re pregnant,your doctor will refer you to an obstetrician or other pregnancy specialist for prenatal care.
• If you’re not pregnant,you’ll stop taking progesterone and likely get your period within a week. If you don’t get your period or you have unusual bleeding, contact your doctor. If you’re interested in attempting another cycle of in vitro fertilization (IVF), your doctor might suggest steps you can take to improve your chances of getting pregnant through IVF.

The chances of giving birth to a healthy baby after using IVF depend on various factors, including:

• Maternal age.The younger you are, the more likely you are to get pregnant and give birth to a healthy baby using your own eggs during IVF. Women age 41 and older are often counselled to consider using donor eggs during IVF to increase the chances of success.
• Embryo status.Transfer of embryos that are more developed is associated with higher pregnancy rates compared with less-developed embryos (day two or three). However, not all embryos survive the development process. Talk with your doctor or other care provider about your specific situation.
• Reproductive history.Women who’ve previously given birth are more likely to be able to get pregnant using IVF than are women who’ve never given birth. Success rates are lower for women who’ve previously used IVF multiple times but didn’t get pregnant.
• Cause of infertility.Having a normal supply of eggs increases your chances of being able to get pregnant using IVF. Women who have severe endometriosis are less likely to be able to get pregnant using IVF than are women who have unexplained infertility.
• Lifestyle factors.Women who smoke typically have fewer eggs retrieved during IVF and may miscarry more often. Smoking can lower a woman’s chance of success using IVF by 50%. Obesity can decrease your chances of getting pregnant and having a baby. Use of alcohol, recreational drugs, excessive caffeine and certain medications also can be harmful.

 Frozen Embryo Transfer:

• A frozen embryo transfer, or FET, is a sort of IVF treatment where a cryopreserved or vitrified embryo made in a full IVF cycle is defrosted or thawed and exchanged to a lady’s uterus. The cryopreserved embryo might be from a patient’s past regular IVF cycle, or it might be a donor embryo.More often than not, a frozen embryo transfer happens when there are “additional” embryos after a regular IVF cycle. However, some doctors are recommending elective frozen embryo transfer — also referred to as a “freeze all” approach. For this situation, all embryos are cryopreserved and moved in a FET cycle in the following month or thereafter.

 Procedure:

The embryo transfer strategy begins by setting a speculum in the vagina to picture the cervix, which is washed down with saline solution or culture media. A delicate embryo transfer catheter is loaded with the embryos and gave to the clinician after confirming the patient details. The catheter is passed through the cervical canal and progressed into the uterine cavity.

There is great and steady proof of advantage in ultrasound direction, that is, making an abdominal ultrasound to ensure correct placement, which is 1–2 cm from the uterine fundus. There is proof of a critical increment in clinical pregnancy utilizing ultrasound direction contrasted and just “clinical touch”.

Anaesthesia is generally not required. Single embryo transfers in particular require accuracy and precision in placement within the uterine cavity.